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19.04.2020 Energy

Vitamin P, as well as hesperidin, catechins, citrine and rutin are a complex of compounds called bioflavonoids. These substances are perfectly soluble in water and are very important for human health. Usually, when it comes to vitamin P, they mean rutin and citrine. But basically they belong to one group - bioflavins.

What are bioflavonoids

Absolutely all bioflavonoids act in almost the same way. These substances reduce capillary fragility and fragility. In other words, their permeability decreases. Hence the name - vitamin R. In fact, this is just an amazing substance.

Once in the human body, P vitamins continue to protect cells. It is on these properties that almost all traditional medicine is based. The molecules of these substances are completely diverse. It is worth noting that the action of the components of the P group can increase the efficiency of some useful elements. For example, the activity of vitamin C is about 20 times.

Vitamin P: which foods contain

Most of this substance is found in citrus fruits. To be more precise, in their interlobular part and white skin. In addition, vitamin P can be found in foods such as grapes, apricots, chokeberries, cherries, rose hips, blackberries, raspberries, and blueberries. As for vegetables, rutin is found in chilli, green lettuce, cilantro, dill, parsley, tomatoes and cabbage. Buckwheat also contains vitamin R. Products that contain this particular component, experts recommend using for varicose veins. After all, this substance perfectly strengthens the walls of blood vessels.

Some drinks and juices also contain this component. Among them: live beer, wine, coffee and tea. As for frozen foods, there is practically no rutin in them.

Vitamin P value

First of all, this substance strengthens and protects the human body. After all, vitamins of group P are distinguished by a fairly high antioxidant activity. For example, green tea contains catechins, which are able to repair damaged cell structure.

In addition, rutin is able to intercept and neutralize most of the free radicals. Daily use of foods that contain vitamin P can significantly strengthen the immune system. After all, this substance protects the body from negative factors, and also prevents early aging and the development of certain diseases.

It should be noted that vitamin P normalizes the capillary structure and constantly maintains it in a normal state. As a result, small vessels become more elastic and, if necessary, can expand without causing the development of ailments.

Bioflavonoids prevent the occurrence of such unpleasant phenomena as changes in blood pressure, poor circulation, edema and varicose veins.

Combination of vitamins P and C

These two components, in combination, are able to prevent the destruction of a substance very important for our body - hyaluronic acid. This component is a kind of cement for capillary and vascular cells. It is this substance that allows them to maintain their strength and structure. This significantly reduces the permeability of the vessel walls and the risk of bruising. Thanks to the P vitamins, the cardiovascular system is completely protected from the effects of cholesterol.

In addition, the interaction of the components allows not only to strengthen the immune system, but also to make more strong defense from colds and some infections. Indeed, the body appears more vitamins of the P group, which have pronounced antibacterial properties.

How much vitamin P should be consumed per day

On the this moment experts have not yet established R. But at the same time they argue that a person gets enough of this component if his diet contains greens, vegetables, berries and fruits.

In some cases, an additional intake of this substance is simply necessary. This is required if there is a severe bruise. Also, this component is needed if bruises remain on the body with light pressure. In such a situation, bioflavonoids should be consumed in combination with vitamin C.

Drugs from the pharmacy

Recently, a lot of different medicines have been created and If there is not enough bioflavonoids, then experts recommend purchasing the drug "Baikalsky" (vitamin P). This product is made from the root part of Siberian larch. The very process of creating this drug is very complex. Only the company LLC "Siberian Cedar" knows all the technology and is able to produce a quality product.

Lack of vitamin P

Due to the lack of this component, capillaries are primarily affected. As a result, this can turn into a very serious illness. Initially, bleeding of the gums may appear, and then hemorrhages in the mucous membranes and skin. As a result, the person becomes more lethargic and weakened. He gets tired very quickly even with light loads. Often, when walking, the legs begin to hurt, and when performing various work with the hands, the shoulders.

A similar condition very often occurs after winter, when there is a need for basic components. Vitamin C also belongs to them. But without it, the use of routine practically does not give results.

When vitamin P enters the body in an insufficient amount, cerebral bleeding can also occur. In addition, diseases of other vital organs, such as the heart and lungs, can develop. It all starts with weakening of the capillaries.

The term "Vitamin P" unites a number of biologically active water-soluble substances (bioflavonoids), which are present in large quantities in the leaves and fruits of many plants in the form of glycosides.

Functions of vitamin P

For the first time bioflavonoids were obtained from lemon peel. To date, over one and a half hundred compounds with similar properties have been discovered.

The most common bioflavonoids include:

rutin;
hesperidin;
quercetin;
citrine;
catechins;
eriodictiol;
cyanidin;
esculin;
anthocyanin.

Note: vitamin P is able to partially cover a person's need for. In this regard, in the medical literature bioflavonoids are often referred to as "vitamin C2".

Bioflavonoids are rather unstable compounds. They tend to break down when food is cooked under the influence of high temperatures and water. In addition, they are inactivated by UV radiation (including solar ultraviolet light).

Bioflavonoids (in particular - catechin) are powerful antioxidants that protect the body from the negative effects of free radicals at the cellular level. Thanks to this, they are able to slow down the natural aging process, significantly strengthen the nonspecific (general) and prevent the onset and development of a number of diseases.

Note:the largest amount of the antioxidant catechin is found in green tea.

Vitamin P increases the body's resistance to adverse exogenous factors.

Vitamin P is called the "capillary permeability factor". It was experimentally found that in combination with ascorbic acid, it helps to strengthen the walls of small blood vessels, increase their elasticity and reduce the degree of permeability. Bioflavonoids prevent vascular hardening and promote vasodilation.

In a person who receives a sufficient amount of vitamin P with food, blood pressure and heart rate normalize, and tissue edema decreases or disappears. Rutin, hesperidin and quercetin are effective in combating scurvy and hemorrhagic diathesis. Active compounds prevent the appearance of intradermal and subcutaneous hematomas ("bruises").

Bioflavonoid compounds increase the absorption of ascorbic acid, potentiate and prolong its action. Catechins strengthen the defenses, increasing the body's resistance to infectious agents of bacterial and viral nature.

Important: the antioxidant activity of quercitin allows. Its effectiveness is especially noticeable in the complex therapy of leukemia and breast cancer! The largest number Quercitin is found in tomatoes and bell peppers.

Bioflavonoids have the ability to slightly stimulate the functional activity of the adrenal cortex, thereby increasing the production of glucocorticoid hormones.

Hesperidin, quercitin and catechin inhibit the biosynthesis and release of the main mediators of allergic reactions. In addition, these bioflavonoids are able to reduce tissue edema and have an analgesic effect. Thus, they reduce the severity of hypersensitivity reactions and facilitate the course of diseases with an allergic component (in particular -).

It has been established that one of the bioflavonoids (quercitin) is able to protect the heart and blood vessels from excess, thus preventing the development of their severe complications (heart attacks and strokes).

Vitamin P is able to regulate daily urine output (urine output) and takes part in the formation of bile.

Where is vitamin P found?

Vitamin P is not synthesized by our body; it can only come in an alimentary way (that is, with food). Since bioflavonoids are not deposited, a person needs to receive them regularly from the outside.

These biologically active compounds are found in the same foods that are the main sources of vitamin C.

Foods high in vitamin P:

Note: The main source of bioflavonoids for the pharmaceutical industry is two types of larch - Daurian and Siberian.

Vitamin P intake rates

Vitamin P must be present in the daily diet. The consumption rates of bioflavonoids for the average adult are:

hesperidin - 100 mg;
rutin - 30 mg;
quercetin - 15 mg.

Note: 100 ml of black chokeberry juice contains about 2000 mg of bioflavonoids. This product is the best source vitamin P!

It has been established that the need for vitamin P increases significantly in smokers, since the combustion products of tobacco reduce the concentration of bioflavonoids in the body.

Indications for vitamin therapy

Clinical studies have shown that vitamin P helps with hypertension and rheumatism. It is also included in the complex therapy of atherosclerosis and some oncological diseases.

The use of quercitin and rutin preparations is indicated if the patient is diagnosed with the following pathologies:

septic endocarditis;
autoimmune inflammation of the arachnoid membrane of the brain (arachnoiditis);
radiation sickness;
thrombocytopenic purpura;
infectious diseases (typhus,).

Vitamin P is prescribed for the prevention and treatment of small vessel lesions caused by the intake of salicylates and anticoagulants.

Interestingly, vitamin P is not a vitamin per se for many reasons. It includes a variety of bioflavonoids. This indicates the broad action of the vitamin.

Vitamin P was discovered by scientist Albert Szent-Gyorgyi in 1936, who received the Nobel Prize for this discovery. Vitamin P is also known as flavonoids.

Scientists have identified over 4,000 flavonoids that are the most naturally concentrated source of nutrients. These are some of the bioflavonoids: quercetin, rutin, myricetin, apigenin, hesperidin, luteolin, catechin, cyanidation and others. Each of them has its own effect on human health, so the range of action of vitamin P on human health is very wide.

Vitamin P action

Rutin is another flavonoid, a component of vitamin P that is currently being actively studied by medicine. In vitro studies have shown that quercetin and rutin have anti-inflammatory properties. They also thin the blood and improve blood circulation. Other scientists are proving that these bioflavonoids can strengthen the walls of blood vessels in the body, which has a positive effect on the circulatory system. Some medical practitioners recommend rutin for a variety of conditions such as hay fever, varicose veins, and glaucoma, but most of these procedures are still experimental.

For vitamin supplements, pharmaceutical manufacturers extract bioflavonoids from citrus fruits. A person can get bioflavonoids from their daily diet by consuming lemons and oranges. Rutin is also found in grapefruits, apricots, plums, and blueberries. Vitamin P-rich vegetables include green and yellow peppers and broccoli, whole grains.

Daily requirement of vitamin P

A daily intake of vitamin P for adults is recommended at a level of 10 to 25 mg.

Vitamin P hypovitaminosis

Deficiency symptoms:

swelling or accumulation of fluid in organs and body systems;
bleeding in the tissue (visible as red spots that are under the skin), which occur through the fragility of the capillaries.

Vitamin P hypervitaminosis

To date, no cases of P. hypervitaminosis have been described in medical practice.

Indications for the use of vitamin P

The use of vitamin P is primarily aimed at treating vitamin P and vitamin C deficiencies, as well as diseases resulting from increased permeability of the vascular walls (retinal hemorrhage, diathesis, hemorrhagic vasculitis, radiation sickness, radiation damage to the skin, septic endocarditis, rheumatism, prevention of bleeding in hypertension, glomerulonephritis, allergic diseases, thrombocytopenic purpura).

Bioflavonoids are used effectively in the treatment of sports injuries as they are excellent pain relievers. They can also be used to relieve pain in the lower extremities and back, and can reduce symptoms of prolonged bleeding, low serum calcium levels, and oral herpes.

Numerous studies on the use of rutin have shown that this nutrient can inhibit histamine, a compound secreted by mast cells. Histamine is produced in large quantities during frequent allergic reactions, including nasal congestion. In fact, rutin is often included in antihistamines.

According to modern complex research, vitamin P in the human body has a good antiviral effect.

Vitamin P also acts as an antiviral agent.

Vitamin P dosages

There are no specific dosage recommendations for vitamin P, but most daily supplements contain between 500 and 1000 mg. Most people can get enough flavonoids from a diet that includes lots of fruits and vegetables. But it is necessary to understand that as a result of cooking and processing food thermally, the concentration of these substances significantly decreases.

There is no evidence of side effects of vitamin supplements, even with very high doses. Some people may be allergic to certain types of bioflavonoids.

Interaction of vitamin P with other compounds and vitamins

This nutrient works with vitamin C to protect the thin walls of the capillaries, thereby preventing bleeding or bruising. Bioflavonoids improve the absorption of ascorbic acid and also enhance its effectiveness. Vitamin P promotes absorption

Vitamin P (rutin and others) - a group of plant flavonoids, which includes such biologically active substances as rutin, rutoside, anthocyanin, hesperidin, catechins, quercetin, cyanidin, citrine, eriodictiol, esculin and others. In total, there are about 150 substances.

Another name for vitamin P is vitamin C2, or C-complex, which is associated with the ability of bioflavonoids to partially cover the deficiency in the body.

Vitamin P got its name from its discoverer, the American biochemist Albert Szent-Gyorgyi, in 1936, who identified this substance from the peel. So, the letter "P" is the first in the word "permeability" (permeability). This word characterizes the role of the vitamin in the vital activity of the body - vitamin P has the property of reducing the fragility and permeability of blood vessels, which has a beneficial effect on the body in case of hemorrhagic diathesis, scurvy and other diseases of the cardiovascular system.

In addition to their main role in strengthening blood vessels, rutin and "Co" play an important role in redox processes, help preserve ascorbic acid, adrenaline and other substances from destruction, and have the ability to neutralize free radicals.

Dosage form of vitamin P - "Troxerutin", "Rutozid", "Rutin", "Ascorutin".

Vitamin P is a water-soluble vitamin-like substance that is also destroyed by heating and freezing, exposure to sunlight, oxygen and tobacco smoke.

Systematic name for routine: 2- (3,4-dihydroxyphenyl) -5,7-dihydroxy-3- [α-L-rhamnopyranosyl- (1 → 6) -β-D-glucopyranosyloxy] -4H-chromen-4-one
C 27 H 30 O 16.
CAS: 153-18-4.

Functions of vitamin P (rutin)

Vitamin P has a number of beneficial properties:

improves the elasticity of blood vessels, as well as reduces their permeability and fragility, which together improves the blood circulation of the body;
prevents blood clots, varicose veins (varicose veins);
keeps ascorbic acid, adrenaline and other substances from oxidation;
is a powerful natural antioxidant;
prevents cells of the body from the destructive effects of free radicals on them;
strengthens the immune system;
normalizes;
regulates the amount of cholesterol in the body;
helps to relieve edema;
in combination with vitamin C prevents the destruction of hyaluronic acid;
thanks to catechins, it has antibacterial and antiviral properties, this is especially true during the increased spread of ARVI, influenza and other acute respiratory infections;
prevents development;
has a beneficial effect on the adrenal cortex, stimulating the production of hormones - glucocorticoids;
slows down the aging process of the body;
hesperidin, catechin, quercetin and other bioflavonoids prevent the production of allergy mediators (histamine, serotonin), which helps to prevent the development of this disease;
improves the course of many diseases, promotes accelerated recovery.

Lack of rutin and other bioflavonoids can cause:

increased susceptibility to the development of: atherosclerosis, varicose veins, thrombosis, stroke, myocardial infarction, arterial hypertension (hypertension) and others;
increased susceptibility to the development of allergic reactions, incl. allergies to house dust, insect bites, pollen, etc .;
increased fatigue;
frequent.
weakening of the immune system.

Daily requirement of vitamin P

Rutin - 30 mg;
Quarcetin - 15 mg;
Hesperidin - 100 mg.

For medicinal purposes, depending on the indications, the daily wash dose can be increased 3-5 times.

Vitamin P supplementation is necessary for:

cardiovascular disease;
infectious diseases;
allergies;
smoking.

Indications for the use of vitamin P

The use of rutin and other substances included in the vitamin P group is relevant in the following situations:

prevention of hypovitaminosis and vitamin P deficiency;
treatment of diseases of the cardiovascular system: thrombosis, varicose veins, septic, thrombocytopenic purpura (Verlhof's disease), capillary toxicosis, hemorrhagic diathesis, microangiopathy, retinal hemorrhages, venous insufficiency of the lower extremities and others;
treatment and prevention of infectious diseases:,, typhus,
treatment of diseases such as -, radiation sickness, arachnoiditis, diabetic retinopathy, lymphedema (lymphostasis);
improving the condition of the blood vessels;
normalization of blood circulation, blood pressure;
prevention of blood clots;
stimulating the immune system;
prevention of adverse reactions from the mucous membrane and skin during radiation therapy;
treatment of chylothorax in dogs and cats.

Dosages for the use of rutoside (rutin)

Rutin is taken orally with water. The dosage depends on the goal pursued:

In case of venous insufficiency: initial dose - 300 mg, 3-4 times a day, daily dose - 1000-1200 mg / day, for 2 weeks;

With diabetic retinopathy: 1000-2000 mg per day;

With lymphedema (lymphostasis): 1000 mg 3 times a day;

For the prevention of dermatological reactions during radiation therapy: 500 mg 2 times a day, during the entire course of radiation;

As a preventive measure against various diseases - 1-2 tablets of 50 mg, 2 times a day.

Contraindications to the use of vitamin P

Hypersensitivity to the substance or I trimester of pregnancy.

Important! During the II and III trimesters of pregnancy, as well as when breastfeeding an infant, the use of vitamin P is also limited and is allowed only with the permission of a doctor.